Protein Information

Cytoscape View

UniProt AC / UniProt ID P22891 / PROZ_HUMAN
Protein Name Vitamin K-dependent protein Z precursor
Gene Name Name: PROZ
Organism Homo sapiens (Human)

PRO ID PR:P22891
DAG View
PRO Name vitamin K-dependent protein Z (human)
Definition A vitamin K-dependent protein Z that is encoded in the genome of human.
Short Label hPROZ
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P22891 (PROZ) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S93 O-Glycosylation GlyGen   UniProt 2129367, 2511201
N99 N-Glycosylation GlyGen   UniProt 20427285
S220 Phosphorylation PhosphoSitePlus
N225 N-Glycosylation GlyGen   UniProt 20427285
N233 N-Glycosylation GlyGen   UniProt 19528533, 20427285
N332 N-Glycosylation GlyGen   UniProt 20427285
S344 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N225 T225 Biomuta DOID:363 / uterine cancer [ tcga ]
N332 I332 Biomuta DOID:363 / uterine cancer [ tcga ]
S344 I344 Biomuta DOID:3571 / liver cancer [ icgc ]