iPTMnet Report for P22830 (FECH)
Protein Information
| UniProt AC / UniProt ID | P22830 / HEMH_HUMAN |
| Protein Name | Ferrochelatase, mitochondrial precursor |
| Gene Name | Name: FECH |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P22830 |
| PRO Name | ferrochelatase, mitochondrial (human) |
| Definition | A ferrochelatase, mitochondrial that is encoded in the genome of human. |
| Short Label | hFECH |
| Category | organism-gene |
DAG ViewP22830 (FECH) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K37 | Acetylation | score1 | PhosphoSitePlus | |||
| T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T116 | Phosphorylation | score0 | RLIMS-P | 28553927 | ||
| S151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y210 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K304 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T315 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S318 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K320 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C323 | Methylation | score1 | IEDB | 31844290 | ||
| K415 | Acetylation | score1 | PhosphoSitePlus | |||
| S420 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S318 | Y318 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] |
