iPTMnet Report for P22760 (AADAC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P22760 / AAAD_HUMAN
Protein Name Arylacetamide deacetylase
Gene Name Name: AADAC
Synonyms:DAC;
Organism Homo sapiens (Human)

PRO ID PR:P22760
DAG View
PRO Name arylacetamide deacetylase (human)
Definition An arylacetamide deacetylase that is encoded in the genome of human.
Short Label hAADAC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P22760 (AADAC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
Y7 Phosphorylation PhosphoSitePlus
Y17 Phosphorylation PhosphoSitePlus
Y18 Phosphorylation PhosphoSitePlus
N78 N-Glycosylation GlyGen   UniProt 24125761, 19159218
Y94 Phosphorylation PhosphoSitePlus
K171 Acetylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
N282 N-Glycosylation GlyGen   UniProt 24125761, 19159218
R290 Methylation PhosphoSitePlus
Y297 Phosphorylation PhosphoSitePlus
Y302 Phosphorylation PhosphoSitePlus
T339 Phosphorylation PhosphoSitePlus
Y342 Phosphorylation PhosphoSitePlus
Y352 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S5 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S5 L5 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
Y17 H17 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y297 S297 Biomuta DOID:1612 / breast cancer [ icgc ]
T339 N339 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]