iPTMnet Report for P22735 (TGM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P22735 / TGM1_HUMAN
Protein Name Protein-glutamine gamma-glutamyltransferase K
Gene Name Name: TGM1
Synonyms:KTG;
Organism Homo sapiens (Human)

PRO ID PR:P22735
DAG View
PRO Name protein-glutamine gamma-glutamyltransferase K (human)
Definition A protein-glutamine gamma-glutamyltransferase K that is encoded in the genome of human.
Short Label hTGM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P22735 (TGM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 8973564
S35 Phosphorylation PhosphoSitePlus
S82 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 8973564
S85 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 8973564
S92 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 8973564
S95 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
Y136 Phosphorylation PhosphoSitePlus
Y267 Phosphorylation PhosphoSitePlus
Y312 Phosphorylation PhosphoSitePlus
Y365 Phosphorylation PhosphoSitePlus
Y370 Phosphorylation PhosphoSitePlus
T525 Phosphorylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
T559 Phosphorylation PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus
Y570 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S755 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S24 C24 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S92 F92 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T525 P525 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T559 I559 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S565 N565 Biomuta DOID:4159 / skin cancer [ cosmic ]