iPTMnet Report for P22692 (IGFBP4)
Protein Information
| UniProt AC / UniProt ID | P22692 / IBP4_HUMAN |
| Protein Name | Insulin-like growth factor-binding protein 4 precursor |
| Gene Name | Name: IGFBP4 Synonyms:IBP4; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P22692 |
| PRO Name | insulin-like growth factor-binding protein 4 (human) |
| Definition | An insulin-like growth factor-binding protein 4 that is encoded in the genome of human. |
| Short Label | hIGFBP4 |
| Category | organism-gene |
DAG ViewP22692 (IGFBP4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N125 | N-Glycosylation | score3 | GlyGen UniProt | 1709161 | ||
| K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S173 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| S255 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 26091039 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S173 | F173 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S255 | N255 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
