Protein Information

Cytoscape View


UniProt AC / UniProt ID P22557 / HEM0_HUMAN
Protein Name 5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor
Gene Name Name: ALAS2
Synonyms:ALASE,ASB;
Organism Homo sapiens (Human)

PRO ID PR:P22557
DAG View
PRO Name 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human)
Definition A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of human.
Short Label hALAS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P22557 (ALAS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T43 Phosphorylation PhosphoSitePlus
K54 Acetylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
T226 Phosphorylation PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K166 N166 Biomuta DOID:363 / uterine cancer [ tcga ]