Protein Information

Cytoscape View


UniProt AC / UniProt ID P22087 / FBRL_HUMAN
Protein Name rRNA 2'-O-methyltransferase fibrillarin
Gene Name Name: FBL
Synonyms:FIB1,FLRN;
Organism Homo sapiens (Human)

PRO ID PR:P22087
DAG View
PRO Name rRNA 2'-O-methyltransferase fibrillarin (human)
Definition An rRNA 2'-O-methyltransferase fibrillarin that is encoded in the genome of human.
Short Label hFBL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P22087 (FBL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
R8 Methylation PhosphoSitePlus
R15 Methylation PhosphoSitePlus
R21 Methylation PhosphoSitePlus
R24 Methylation PhosphoSitePlus
R27 Methylation PhosphoSitePlus
R34 Methylation PhosphoSitePlus
R36 Methylation PhosphoSitePlus
R45 Methylation PhosphoSitePlus
R59 Methylation PhosphoSitePlus
R70 Methylation PhosphoSitePlus
R72 Methylation PhosphoSitePlus
R78 Methylation PhosphoSitePlus
C99 S-Nitrosylation dbSNO 19483679, 26338901
K102 Acetylation PhosphoSitePlus
K102 Sumoylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K109 Sumoylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y118 Phosphorylation PhosphoSitePlus
K121 Acetylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
S124 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...19007248, 19691289, 19651622, 18669648, 24275569, 20068231
S126 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 23186163, 18452278
K131 Ubiquitination PhosphoSitePlus
K143 Sumoylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K158 Sumoylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K205 Acetylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K206 Acetylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
T208 Phosphorylation HPRD   PhosphoSitePlus 20068231
K222 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
Y302 Phosphorylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus