iPTMnet Report for P22079 (LPO)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P22079 / PERL_HUMAN
Protein Name Lactoperoxidase precursor
Gene Name Name: LPO
Synonyms:SAPX;
Organism Homo sapiens (Human)

PRO ID PR:P22079
DAG View
PRO Name lactoperoxidase (human)
Definition A lactoperoxidase that is encoded in the genome of human.
Short Label hLPO
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P22079 (LPO) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
N212 N-Glycosylation GlyGen   UniProt 16740002
N322 N-Glycosylation GlyGen 32125861
N358 N-Glycosylation GlyGen   UniProt 16740002, 18780401
S374 Phosphorylation PhosphoSitePlus
T384 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
T461 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
K537 Acetylation PhosphoSitePlus
S705 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S35 F35 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S35 C35 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
N358 S358 Biomuta DOID:1324 / lung cancer [ cosmic ]
K537 N537 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]