Protein Information

Cytoscape View


UniProt AC / UniProt ID P21980 / TGM2_HUMAN
Protein Name Protein-glutamine gamma-glutamyltransferase 2
Gene Name Name: TGM2
Organism Homo sapiens (Human)

PRO ID PR:P21980
DAG View
PRO Name protein-glutamine gamma-glutamyltransferase 2 (human)
Definition A protein-glutamine gamma-glutamyltransferase 2 that is encoded in the genome of human.
Short Label hTGM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21980 (TGM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
C10 S-Nitrosylation dbSNO 22178444, 11305905
C27 S-Nitrosylation dbSNO 22178444, 11305905
S56 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus   UniProt 24275569
C98 S-Nitrosylation dbSNO 22178444, 11305905
S129 Phosphorylation RLIMS-P 22389828
C143 S-Nitrosylation dbSNO 22178444, 11305905
Y159 Phosphorylation PhosphoSitePlus
K202 Acetylation PhosphoSitePlus
K205 Acetylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
S215 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 16870138
S216 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   RLIMS-P 22759359, 16870138
Y219 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
C230 S-Nitrosylation dbSNO 22178444, 11305905
Y245 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
C269 S-Nitrosylation dbSNO 22178444, 11305905
C277 S-Nitrosylation dbSNO 22178444, 11305905
C285 S-Nitrosylation dbSNO 22178444, 11305905
Y315 Phosphorylation PhosphoSitePlus
C336 S-Nitrosylation dbSNO 22178444, 11305905
T368 Phosphorylation PhosphoSitePlus
Y369 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455, 18083107
C370 S-Nitrosylation dbSNO 22178444, 2212679, 22126794, ...11305905
C371 S-Nitrosylation dbSNO 22178444, 2212679, 22126794, ...11305905
S415 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
C524 S-Nitrosylation dbSNO 22178444, 2212679, 22126794, ...11305905
S538 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
C545 S-Nitrosylation dbSNO 22178444, 11305905
C554 S-Nitrosylation dbSNO 2212679, 22126794
Y575 Phosphorylation PhosphoSitePlus
Y583 Phosphorylation PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
C620 S-Nitrosylation dbSNO 22178444, 11305905
K649 Ubiquitination PhosphoSitePlus
K672 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S216 Phosphorylation HPRD 20166139
Y219 Phosphorylation HPRD 18083107
Y369 Phosphorylation HPRD 15592455, 18083107
Site PTM Type PTM Enzyme Score Source PMID
S216 Phosphorylation HPRD 20166139
Y219 Phosphorylation HPRD 18083107
Y369 Phosphorylation HPRD 15592455, 18083107


P21980 (TGM2) as PTM Enzyme



Substrate Site Score Source PMID
P68431 (H3C12) S11 Signor 16407273


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P04637 (TP53) S15 P21980 (TGM2) unknown eFIP 27031960