iPTMnet Report for P21815 (IBSP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P21815 / SIAL_HUMAN
Protein Name Bone sialoprotein 2 precursor
Gene Name Name: IBSP
Synonyms:BNSP;
Organism Homo sapiens (Human)

PRO ID PR:P21815
DAG View
PRO Name bone sialoprotein 2 (human)
Definition A bone sialoprotein 2 that is encoded in the genome of human.
Short Label hIBSP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21815 (IBSP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus   UniProt 11669636
Y39 Phosphorylation PhosphoSitePlus
T119 O-Glycosylation GlyGen   UniProt 11459848
T122 O-Glycosylation GlyGen   UniProt 11459848
T207 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
T227 O-Glycosylation GlyGen   UniProt 11459848
T228 O-Glycosylation GlyGen   UniProt 11459848
T228 Phosphorylation PhosphoSitePlus
T229 O-Glycosylation GlyGen   UniProt 11459848
T238 O-Glycosylation GlyGen   UniProt 11459848
T239 O-Glycosylation GlyGen   UniProt 11459848
T246 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T3 A3 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S31 Y31 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T119 M119 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T207 I207 Biomuta DOID:3571 / liver cancer [ cosmic ]
S225 L225 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
T238 A238 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T239 P239 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]