iPTMnet Report for P21754 (ZP3)
Protein Information
| UniProt AC / UniProt ID | P21754 / ZP3_HUMAN |
| Protein Name | Zona pellucida sperm-binding protein 3 precursor |
| Gene Name | Name: ZP3 Synonyms:ZP3A,ZP3B,ZPC; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P21754 |
| PRO Name | zona pellucida sperm-binding protein 3 (human) |
| Definition | A zona pellucida sperm-binding protein 3 that is encoded in the genome of human. |
| Short Label | hZP3 |
| Category | organism-gene |
DAG ViewP21754 (ZP3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N125 | N-Glycosylation | score3 | GlyGen UniProt | 15379548 | ||
| N147 | N-Glycosylation | score3 | GlyGen UniProt | 15379548 | ||
| S149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S150 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T156 | O-Glycosylation | score2 | GlyGen | 16401092 | ||
| K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N272 | N-Glycosylation | score3 | GlyGen UniProt | 15379548 | ||
| K298 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K64 | N64 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| N125 | H125 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S150 | I150 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| K185 | R185 | Biomuta | DOID:2021 / placenta cancer [ cosmic ] |
