Protein Information

Cytoscape View


UniProt AC / UniProt ID P21728 / DRD1_HUMAN
Protein Name D(1A) dopamine receptor
Gene Name Name: DRD1
Organism Homo sapiens (Human)

PRO ID PR:P21728
DAG View
PRO Name D(1A) dopamine receptor (human)
Definition A D(1A) dopamine receptor that is encoded in the genome of human.
Short Label hDRD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21728 (DRD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S56 Phosphorylation PhosphoSitePlus
T136 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
T245 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
T360 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 11773080
T428 Phosphorylation PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S258 N258 Biomuta DOID:3070 / malignant glioma [ tcga ]
S259 F259 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S259 Y259 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T360 K360 Biomuta DOID:1324 / lung cancer [ cosmic ]