Protein Information

Cytoscape View


UniProt AC / UniProt ID P21675 / TAF1_HUMAN
Protein Name Transcription initiation factor TFIID subunit 1
Gene Name Name: TAF1
Synonyms:BA2R,CCG1,CCGS,TAF2A;
Organism Homo sapiens (Human)

PRO ID PR:P21675
DAG View
PRO Name transcription initiation factor TFIID subunit 1 (human)
Definition A transcription initiation factor TFIID subunit 1 that is encoded in the genome of human.
Short Label hTAF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21675 (TAF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S137 Phosphorylation P21675 (TAF1) PhosphoSitePlus   UniProt 8625415
T198 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
S307 Phosphorylation P21675 (TAF1) PhosphoSitePlus   UniProt 8625415, 24275569
S324 Phosphorylation PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
Y350 Phosphorylation PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
T521 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18452278
S522 Phosphorylation HPRD   PhosphoSitePlus 18452278
S524 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15302935, 20068231, 18452278
S526 Phosphorylation HPRD   PhosphoSitePlus 18452278
K549 Sumoylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
K701 Ubiquitination PhosphoSitePlus
K705 Acetylation PhosphoSitePlus
K705 Ubiquitination PhosphoSitePlus
K832 Ubiquitination PhosphoSitePlus
T855 Phosphorylation PhosphoSitePlus
Y888 Phosphorylation PhosphoSitePlus
Y889 Phosphorylation PhosphoSitePlus
K986 Ubiquitination PhosphoSitePlus
K1009 Ubiquitination PhosphoSitePlus
S1054 Phosphorylation PhosphoSitePlus
K1111 Ubiquitination PhosphoSitePlus
S1118 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
T1150 Phosphorylation HPRD   PhosphoSitePlus 20068231, 18452278
S1152 Phosphorylation PhosphoSitePlus
T1154 Phosphorylation HPRD 20068231
S1155 Phosphorylation HPRD   PhosphoSitePlus 18452278
S1158 Phosphorylation PhosphoSitePlus
K1208 Ubiquitination PhosphoSitePlus
K1244 Acetylation PhosphoSitePlus
T1306 Phosphorylation PhosphoSitePlus
K1327 Ubiquitination PhosphoSitePlus
S1340 Phosphorylation PhosphoSitePlus
K1347 Acetylation PhosphoSitePlus
K1354 Acetylation PhosphoSitePlus
T1360 Phosphorylation PhosphoSitePlus
Y1366 Phosphorylation PhosphoSitePlus
T1379 Phosphorylation PhosphoSitePlus
T1384 Phosphorylation PhosphoSitePlus
S1391 Phosphorylation PhosphoSitePlus
Y1541 Phosphorylation PhosphoSitePlus
Y1562 Phosphorylation PhosphoSitePlus
S1564 Phosphorylation PhosphoSitePlus
S1633 Phosphorylation PhosphoSitePlus
T1643 Phosphorylation PhosphoSitePlus   RLIMS-P 26769797
T1654 O-Glycosylation GlyGen 30459171
S1669 Phosphorylation PhosphoSitePlus
S1672 Phosphorylation PhosphoSitePlus
S1678 Phosphorylation PhosphoSitePlus
T1680 Phosphorylation HPRD   PhosphoSitePlus 20068231, 18452278
S1799 Phosphorylation PhosphoSitePlus
S1802 Phosphorylation PhosphoSitePlus
S1826 Phosphorylation PhosphoSitePlus   UniProt 19690332
Site PTM Type PTM Enzyme Score Source PMID
K170 Acetylation PhosphoSitePlus
K726 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1697 Phosphorylation PhosphoSitePlus


P21675 (TAF1) as PTM Enzyme



Substrate Site Score Source PMID
P04637 (TP53) T55 PhosphoSitePlus   Signor 17245430, 24289924, 15053879
P21675 (TAF1) S137 UniProt 8625415
P21675 (TAF1) S307 UniProt 8625415
P52655-2 (GTF2A1) S241 HPRD 11278496
P52655-2 (GTF2A1) S242 HPRD 11278496
P52655-2 (GTF2A1) S277 HPRD 11278496, 18452278
P52655 (GTF2A1) S280 HPRD   Signor 11278496
P52655-1 (GTF2A1) S281 HPRD   Signor 11278496
P52655-2 (GTF2A1) S282 HPRD 11278496, 18452278
P52655 (GTF2A1) S316 HPRD   PhosphoSitePlus   Signor 11278496, 18452278
P52655 (GTF2A1) S321 HPRD   PhosphoSitePlus   Signor 11278496, 18452278
Q15545 (TAF7) S264 PhosphoSitePlus 22711989


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S137 L137 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S202 F202 Biomuta DOID:1324 / lung cancer [ tcga ]
S324 * Biomuta DOID:1324 / lung cancer [ tcga ]
Y364 C364 Biomuta DOID:1909 / melanoma [ cosmic ]
S524 P524 Biomuta DOID:3277 / thymus cancer [ tcga ] DOID:3571 / liver cancer [ tcga ]
K701 N701 Biomuta DOID:363 / uterine cancer [ tcga ]
K701 R701 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K832 Q832 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K1009 T1009 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K1111 E1111 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S1118 L1118 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
Y1366 C1366 Biomuta DOID:1324 / lung cancer [ tcga ]
T1384 M1384 Biomuta DOID:363 / uterine cancer [ tcga ]
S1672 Y1672 Biomuta DOID:10283 / prostate cancer [ cosmic ]