Protein Information

Cytoscape View


UniProt AC / UniProt ID P21549 / AGT1_HUMAN
Protein Name Alanine--glyoxylate aminotransferase
Gene Name Name: AGXT
Synonyms:AGT1,SPAT;
Organism Homo sapiens (Human)

PRO ID PR:P21549
DAG View
PRO Name alanine--glyoxylate aminotransferase (human)
Definition An alanine--glyoxylate aminotransferase that is encoded in the genome of human.
Short Label hAGXT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21549 (AGXT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus   UniProt 24275569
S81 Phosphorylation PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
K228 Methylation PhosphoSitePlus
Y231 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
Y297 Phosphorylation PhosphoSitePlus
K389 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K228 Q228 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K228 * Biomuta DOID:4159 / skin cancer [ cosmic ]