iPTMnet Report for P21439 (ABCB4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P21439 / MDR3_HUMAN
Protein Name Phosphatidylcholine translocator ABCB4
Gene Name Name: ABCB4
Synonyms:MDR3;
Organism Homo sapiens (Human)

PRO ID PR:P21439
DAG View
PRO Name phosphatidylcholine translocator ABCB4 (human)
Definition A phosphatidylcholine translocator ABCB4 that is encoded in the genome of human.
Short Label hABCB4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21439 (ABCB4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T34 Phosphorylation UniProt 24723470
S121 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
T524 Phosphorylation PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
Y624 Phosphorylation PhosphoSitePlus
K679 Acetylation PhosphoSitePlus
K699 Acetylation PhosphoSitePlus
K1061 Ubiquitination PhosphoSitePlus
K1178 Ubiquitination PhosphoSitePlus
K1187 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T34 M34 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T34 R34 Biomuta DOID:4159 / skin cancer [ cosmic ]
K413 * Biomuta DOID:1612 / breast cancer [ cosmic ]
T524 A524 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y624 H624 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K679 M679 Biomuta DOID:363 / uterine cancer [ icgc ]