Protein Information

Cytoscape View


UniProt AC / UniProt ID P21266 / GSTM3_HUMAN
Protein Name Glutathione S-transferase Mu 3
Gene Name Name: GSTM3
Synonyms:GST5;
Organism Homo sapiens (Human)

PRO ID PR:P21266
DAG View
PRO Name glutathione S-transferase mu 3 (human)
Definition A glutathione S-transferase mu 3 that is encoded in the genome of human.
Short Label hGSTM3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P21266 (GSTM3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
C39 S-Nitrosylation dbSNO 19483679
R47 Methylation PhosphoSitePlus
K54 Sumoylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
Y66 Phosphorylation PhosphoSitePlus
K71 Acetylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
T75 Phosphorylation HPRD   PhosphoSitePlus 20068231
R82 Methylation PhosphoSitePlus
K87 Acetylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
K128 Sumoylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
C208 S-Nitrosylation dbSNO 19483679
K209 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R47 * Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ]
R47 Q47 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K73 N73 Biomuta DOID:3070 / malignant glioma [ tcga ]
R82 H82 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R82 C82 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S143 Y143 Biomuta DOID:3571 / liver cancer [ icgc ]
S204 A204 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]