iPTMnet Report P20941 PDC

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P20941 / PHOS_HUMAN
Protein Name	Phosducin
Gene Name	Name: PDC
Organism	Homo sapiens (Human)

PRO ID	PR:P20941 DAG View
PRO Name	phosducin (human)
Definition	A phosducin that is encoded in the genome of human.
Short Label	hPDC
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P20941 (PDC) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S36	Phosphorylation		score1	PhosphoSitePlus
	S54	Phosphorylation		score1	RLIMS-P	11331285, 15485848, 23199924
	K62	Acetylation		score1	PhosphoSitePlus
	K65	Acetylation		score1	PhosphoSitePlus
	S73	Phosphorylation		score4	neXtProt RLIMS-P	10360181, 11331285, 23199924, ...15485848, 1659528, 17569665, 9020189
	S106	Phosphorylation		score0	RLIMS-P	15485848
	Y141	Phosphorylation		score1	IEDB	35494241

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S54	Phosphorylation	Q9UQM7 (CAMK2A)	score1	HPRD	11331285
	S73	Phosphorylation	P17612 (PRKACA) , Q9UQM7 (CAMK2A)	score2	HPRD	11331285, 2394752

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S2	Phosphorylation	Q9UQM7 (CAMK2A)	score1	HPRD	11331285
	S21	Phosphorylation	P17612 (PRKACA) , Q9UQM7 (CAMK2A)	score2	HPRD	11331285, 2394752

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S2	P2	Biomuta		DOID:363 / uterine cancer [ icgc ]
S36	N36	Biomuta		DOID:9256 / colorectal cancer [ cosmic, icgc ]
S54	P54	Biomuta		DOID:363 / uterine cancer [ icgc ]