Protein Information

Cytoscape View


UniProt AC / UniProt ID P20853 / CP2A7_HUMAN
Protein Name Cytochrome P450 2A7
Gene Name Name: CYP2A7
Organism Homo sapiens (Human)

PRO ID PR:P20853
DAG View
PRO Name cytochrome P450 2A7 (human)
Definition A cytochrome P450 2A that is a translation product of the CYP2A7 gene in human.
Short Label hCYP2A7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20853 (CYP2A7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S175 Phosphorylation PhosphoSitePlus
T177 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
Y351 Phosphorylation PhosphoSitePlus
K436 Acetylation PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
T488 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T177 A177 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S183 T183 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T482 R482 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]
T482 K482 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]