iPTMnet Report for P20853 (CYP2A7)
Protein Information
| UniProt AC / UniProt ID | P20853 / CP2A7_HUMAN |
| Protein Name | Cytochrome P450 2A7 |
| Gene Name | Name: CYP2A7 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P20853 |
| PRO Name | cytochrome P450 2A7 (human) |
| Definition | A cytochrome P450 2A that is a translation product of the CYP2A7 gene in human. |
| Short Label | hCYP2A7 |
| Category | organism-gene |
DAG ViewP20853 (CYP2A7) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S175 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T177 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y351 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K436 | Acetylation | score1 | PhosphoSitePlus | |||
| T482 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T488 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T177 | A177 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S183 | T183 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S184 | F184 | Biomuta | [ cosmic ] | |
| T482 | R482 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| T482 | K482 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
