iPTMnet Report for P20851 (C4BPB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P20851 / C4BPB_HUMAN
Protein Name C4b-binding protein beta chain precursor
Gene Name Name: C4BPB
Organism Homo sapiens (Human)

PRO ID PR:P20851
DAG View
PRO Name C4b-binding protein beta chain (human)
Definition A C4b-binding protein beta chain that is encoded in the genome of human.
Short Label hC4BPB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20851 (C4BPB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K58 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
N64 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 14760718, ...29391424, 29741879, 29671580
K67 Ubiquitination PhosphoSitePlus
N71 N-Glycosylation GlyGen   UniProt 23090970, 14760718, 29671580, ...29391424
N98 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 23090970, ...14760718, 29741879, 29671580
K102 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
N154 N-Glycosylation GlyGen 29741879
T160 O-Glycosylation GlyGen 30459171
K199 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
N214 N-Glycosylation GlyGen 29391424
K227 Ubiquitination PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N64 N-Glycosylation PRO 29671580
N71 N-Glycosylation PRO 29671580
N98 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K102 E102 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K102 N102 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
N154 T154 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K237 * Biomuta DOID:4159 / skin cancer [ cosmic ]