iPTMnet Report for P20815 (CYP3A5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P20815 / CP3A5_HUMAN
Protein Name Cytochrome P450 3A5
Gene Name Name: CYP3A5
Organism Homo sapiens (Human)

PRO ID PR:P20815
DAG View
PRO Name cytochrome P450 3A5 (human)
Definition A cytochrome P450 3A5 that is encoded in the genome of human.
Short Label hCYP3A5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20815 (CYP3A5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T85 Phosphorylation IEDB 35494241
Y99 Phosphorylation PhosphoSitePlus
K127 Acetylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
S278 O-Glycosylation GlyGen 36240223
Y347 Phosphorylation PhosphoSitePlus
S392 Phosphorylation neXtProt 8034584
Site PTM Type PTM Enzyme Score Source PMID
Y347 Phosphorylation HPRD 20058876
Site PTM Type PTM Enzyme Score Source PMID
T110 Phosphorylation PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T110 M110 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
K127 N127 Biomuta DOID:1612 / breast cancer [ cosmic ]
S278 Y278 Biomuta DOID:4606 / bile duct cancer [ cosmic ]