iPTMnet Report for P20813 (CYP2B6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P20813 / CP2B6_HUMAN
Protein Name Cytochrome P450 2B6
Gene Name Name: CYP2B6
Organism Homo sapiens (Human)

PRO ID PR:P20813
DAG View
PRO Name cytochrome P450 2B6 (human)
Definition A cytochrome P450 2B6 that is encoded in the genome of human.
Short Label hCYP2B6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20813 (CYP2B6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S128 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus 2583091
S207 Phosphorylation IEDB 35494241
S277 Phosphorylation IEDB 35494241
K433 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S128 Phosphorylation HPRD 90059885


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S128 C128 Biomuta DOID:1324 / lung cancer [ cosmic ]
S207 L207 Biomuta DOID:4159 / skin cancer [ cosmic ]
S277 F277 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K433 T433 Biomuta DOID:3571 / liver cancer [ cosmic ]