iPTMnet Report P20794 MAK

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P20794 / MAK_HUMAN
Protein Name	Serine/threonine-protein kinase MAK
Gene Name	Name: MAK
Organism	Homo sapiens (Human)

PRO ID	PR:P20794 DAG View
PRO Name	serine/threonine-protein kinase MAK (human)
Definition	A serine/threonine-protein kinase MAK that is encoded in the genome of human.
Short Label	hMAK
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P20794 (MAK) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y156	Phosphorylation		score1	PhosphoSitePlus
	T157	Phosphorylation		score3	PhosphoSitePlus Signor UniProt	21986944
	T157	Phosphorylation	P20794 (MAK)	score3	Signor UniProt	21986944
	Y159	Phosphorylation		score3	PhosphoSitePlus Signor UniProt	21986944
	Y159	Phosphorylation	P20794 (MAK)	score3	Signor UniProt	21986944
	S161	Phosphorylation		score1	PhosphoSitePlus
	T162	Phosphorylation		score1	PhosphoSitePlus
	S457	Phosphorylation		score1	PhosphoSitePlus
	S476	Phosphorylation		score1	PhosphoSitePlus
	Y480	Phosphorylation		score1	PhosphoSitePlus
	S510	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T5	Phosphorylation		score0	HPRD	20068231

P20794 (MAK) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	P20794 (MAK)	T157	score3	Signor UniProt	21986944
	P20794 (MAK)	Y159	score3	Signor UniProt	21986944

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S457	R457	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
Y480	C480	Biomuta		DOID:10283 / prostate cancer [ cosmic, icgc ]