iPTMnet Report for P20749 (BCL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P20749 / BCL3_HUMAN
Protein Name B-cell lymphoma 3 protein
Gene Name Name: BCL3
Synonyms:BCL4,D19S37;
Organism Homo sapiens (Human)

PRO ID PR:P20749
DAG View
PRO Name B-cell lymphoma 3 protein (human)
Definition A B-cell lymphoma 3 protein that is encoded in the genome of human.
Short Label hBCL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20749 (BCL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K21 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
S41 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17322306, 23186163
R78 Methylation PhosphoSitePlus
Y83 Phosphorylation PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
C254 Methylation IEDB 31844290
K338 Methylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus   UniProt 23186163
S386 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus   UniProt 15469820
S402 Phosphorylation P49840 (GSK3A) PhosphoSitePlus 15469820
S406 Phosphorylation PhosphoSitePlus   UniProt 15469820
S406 Phosphorylation P49840 (GSK3A) PhosphoSitePlus 15469820
S448 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y83 F83 Biomuta DOID:10534 / stomach cancer [ icgc ]
K338 Q338 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S374 C374 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S448 F448 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S454 C454 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]