iPTMnet Report for P20702 (ITGAX)
Protein Information
| UniProt AC / UniProt ID | P20702 / ITAX_HUMAN |
| Protein Name | Integrin alpha-X precursor |
| Gene Name | Name: ITGAX Synonyms:CD11C; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P20702 |
| PRO Name | integrin alpha-X (human) |
| Definition | An integrin alpha-X that is encoded in the genome of human. |
| Short Label | hITGAX |
| Category | organism-gene |
DAG ViewP20702 (ITGAX) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N61 | N-Glycosylation | score3 | GlyGen UniProt | 20033057 | ||
| N392 | N-Glycosylation | score3 | GlyGen UniProt | 20033057 | ||
| S668 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 | ||
| S673 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S674 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N697 | N-Glycosylation | score3 | GlyGen UniProt | 20033057 | ||
| N735 | N-Glycosylation | score4 | GlyGen UniProt | 29741879, 20033057 | ||
| N899 | N-Glycosylation | score4 | GlyGen UniProt | 29741879, 20033057, 19159218, ... | ||
| N939 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
| N1050 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S1158 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 24129562 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S668 | N668 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S1158 | G1158 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S1158 | R1158 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S1158 | I1158 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |
