iPTMnet Report for P20700 (LMNB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P20700 / LMNB1_HUMAN
Protein Name Lamin-B1 precursor
Gene Name Name: LMNB1
Synonyms:LMN2,LMNB;
Organism Homo sapiens (Human)

PRO ID PR:P20700
DAG View
PRO Name lamin-B1 (human)
Definition A lamin-B1 that is encoded in the genome of human.
Short Label hLMNB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20700 (LMNB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895, 20068231
T3 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19691289, 20068231
T5 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 20068231
R10 Methylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
R14 Methylation PhosphoSitePlus   UniProt 24129315
T19 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 17081983, 19664995, ...19691289, 18669648, 20068231
T20 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 17081983, ...23186163, 16964243, 18767875, 19664995, 16565220, 19651622, 18669648, 24275569, 19415658, 20068231, 19691289
S23 Phosphorylation P06493 (CDK1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16964243, 18691976, 21406692, ...23186163, 8034666, 18234856, 19691289, 16565220, 24275569, 19413330, 18767875, 20058876, 19007248, 19651622, 2188730, 17287340, 17081983, 19664994, 19664995, 18669648, 19415658, 20068231
T25 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 23186163, 17081983, ...20068231
S28 O-Glycosylation GlyGen 33214551, 34725712, 30444036, ...30379171, 32522876, 28411811, 29351928, 34019948, 22967762, 32119511, 28510447, 22121020
S28 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
K33 Acetylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
R42 Methylation PhosphoSitePlus
Y46 Phosphorylation PhosphoSitePlus
K49 Acetylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
T84 Phosphorylation PhosphoSitePlus
K102 Acetylation PhosphoSitePlus
K102 Sumoylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K111 Acetylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
Y138 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
K157 Acetylation PhosphoSitePlus   UniProt 19608861
K157 Ubiquitination PhosphoSitePlus
S158 Phosphorylation HPRD   PhosphoSitePlus 20068231
K167 Ubiquitination PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
R197 Methylation PhosphoSitePlus
C198 S-Nitrosylation dbSNO 26338901
S200 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
K209 Acetylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S210 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
Y212 Phosphorylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
S232 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19691289
Y238 Phosphorylation PhosphoSitePlus
K241 Sumoylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
R250 Methylation PhosphoSitePlus
K261 Sumoylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
T267 Phosphorylation PhosphoSitePlus
Y268 Phosphorylation PhosphoSitePlus
K271 Acetylation PhosphoSitePlus   UniProt 19608861
K271 Ubiquitination PhosphoSitePlus
S278 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19007248, 20068231, ...19691289
S279 Phosphorylation HPRD   PhosphoSitePlus 19007248
T283 Phosphorylation PhosphoSitePlus
S284 Phosphorylation HPRD   PhosphoSitePlus 18669648, 19007248, 20068231, ...19691289
T285 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
R297 Methylation PhosphoSitePlus
R299 Methylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus   UniProt 23186163
S304 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
K312 Acetylation PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
S375 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19690332, 20068231, ...19691289
Y377 Phosphorylation PhosphoSitePlus
K379 Acetylation PhosphoSitePlus
K379 Sumoylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
R387 Methylation PhosphoSitePlus
K389 Acetylation PhosphoSitePlus
K389 Sumoylation PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
S391 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 16083285, 28542436, 17081983, ...18767875, 19007248, 16565220, 19651622, 20068231
S393 Phosphorylation P06493 (CDK1) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 2188730, 16083285, 28542436, ...17081983, 8034666, 18767875, 16565220, 19651622, 20068231, 20068230
S395 Phosphorylation P05771-2 (PRKCB) HPRD   phospho.ELM   PhosphoSitePlus 20068231, 8034666, 8463284
S396 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 8463284, 20068231
T399 Phosphorylation PhosphoSitePlus
S401 O-Glycosylation GlyGen 33214551, 34725712, 30444036, ...30379171, 32522876, 28411811, 29351928, 34019948, 22967762, 32119511, 28510447, 22121020
S401 Phosphorylation PhosphoSitePlus
S404 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983, 20068231
S405 Phosphorylation P05771 (PRKCB) HPRD   phospho.ELM   PhosphoSitePlus   Signor 8034666, 8463284
S406 Phosphorylation phospho.ELM   PhosphoSitePlus 8463284
S408 Phosphorylation PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
K474 Acetylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
K483 Acetylation PhosphoSitePlus   UniProt 19608861
K483 Ubiquitination PhosphoSitePlus
S508 Phosphorylation RLIMS-P 28542436
K528 Ubiquitination PhosphoSitePlus
K532 Acetylation PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
S534 Phosphorylation IEDB   PhosphoSitePlus   UniProt 32387766, 23186163
K547 Ubiquitination PhosphoSitePlus
T575 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 17081983, ...19664995, 19651622, 18669648, 24275569, 28542436, 20068231
S579 Phosphorylation HPRD 19007248