iPTMnet Report P20645 M6PR

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P20645 / MPRD_HUMAN
Protein Name	Cation-dependent mannose-6-phosphate receptor precursor
Gene Name	Name: M6PR Synonyms:MPR46,MPRD;
Organism	Homo sapiens (Human)

PRO ID	PR:P20645 DAG View
PRO Name	cation-dependent mannose-6-phosphate receptor (human)
Definition	A cation-dependent mannose-6-phosphate receptor that is encoded in the genome of human.
Short Label	hM6PR
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P20645 (M6PR) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K44	Ubiquitination		score1	PhosphoSitePlus
	K50	Ubiquitination		score1	PhosphoSitePlus
	N57	N-Glycosylation		score1	GlyGen	23090970, 29741879, 24190977
	N83	N-Glycosylation		score2	GlyGen UniProt	23090970, 29741879, 19159218, ...24190977
	N107	N-Glycosylation		score2	GlyGen UniProt	19159218, 24190977
	N113	N-Glycosylation		score1	GlyGen	24190977
	N116	N-Glycosylation		score1	GlyGen	24190977
	Y255	Phosphorylation		score1	PhosphoSitePlus
	S267	Phosphorylation		score2	HPRD phospho.ELM PhosphoSitePlus	18669648

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N57	N-Glycosylation		score1	PRO	29741879

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K50	M50	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
Y255	F255	Biomuta		DOID:8618 / oral cavity cancer [ cosmic ]