iPTMnet Report for P20618 (PSMB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P20618 / PSB1_HUMAN
Protein Name Proteasome subunit beta type-1 precursor
Gene Name Name: PSMB1
Synonyms:PSC5;
Organism Homo sapiens (Human)

PRO ID PR:P20618
DAG View
PRO Name proteasome subunit beta type-1 (human)
Definition A proteasome subunit beta type-1 that is encoded in the genome of human.
Short Label hPSMB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20618 (PSMB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
Y8 Phosphorylation PhosphoSitePlus
S62 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
T65 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus   UniProt 23186163
K70 Acetylation PhosphoSitePlus
C71 Methylation IEDB 31844290
K73 Ubiquitination PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
C82 S-Nitrosylation dbSNO 19483679
S83 Phosphorylation PhosphoSitePlus
C89 Methylation IEDB 31844290
C89 S-Nitrosylation dbSNO 19483679
T91 Phosphorylation PhosphoSitePlus
T93 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
S106 O-Glycosylation GlyGen 33214551, 35138101, 34725712, ...33465208, 34019948, 34229054
Y125 Phosphorylation PhosphoSitePlus
Y132 Phosphorylation PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus   UniProt 23186163
K164 Ubiquitination PhosphoSitePlus
K184 Acetylation PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
K204 Acetylation PhosphoSitePlus   UniProt 19608861
K204 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
C224 S-Nitrosylation dbSNO 19483679
K228 Acetylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
R239 Methylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y8 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S62 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T65 M65 Biomuta DOID:4159 / skin cancer [ cosmic ]
T65 R65 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S106 A106 Biomuta DOID:363 / uterine cancer [ icgc ]
K184 N184 Biomuta DOID:363 / uterine cancer [ icgc ]
K228 E228 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]