Protein Information

Cytoscape View


UniProt AC / UniProt ID P20591 / MX1_HUMAN
Protein Name Interferon-induced GTP-binding protein Mx1
Gene Name Name: MX1
Organism Homo sapiens (Human)

PRO ID PR:P20591
DAG View
PRO Name interferon-induced GTP-binding protein Mx1 (human)
Definition An interferon-induced GTP-binding protein Mx1 that is encoded in the genome of human.
Short Label hMX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20591 (MX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
Y129 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y196 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K359 Ubiquitination PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
Y451 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K459 Ubiquitination PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
K505 Ubiquitination PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S84 Phosphorylation HPRD 20068231
S85 Phosphorylation HPRD 20068231
Y129 Phosphorylation HPRD 18083107
Y451 Phosphorylation HPRD 18083107


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:Q9HCX4 (hTRPC7) Interaction PR:P20591 (hMX1) PRO 15757897


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K490 T490 Biomuta DOID:363 / uterine cancer [ tcga ]
S558 F558 Biomuta DOID:363 / uterine cancer [ tcga ]
K631 M631 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]