iPTMnet Report for P20585 (MSH3)
Protein Information
| UniProt AC / UniProt ID | P20585 / MSH3_HUMAN |
| Protein Name | DNA mismatch repair protein Msh3 |
| Gene Name | Name: MSH3 Synonyms:DUC1,DUG; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P20585 |
| PRO Name | DNA mismatch repair protein Msh3 (human) |
| Definition | A DNA mismatch repair protein Msh3 that is encoded in the genome of human. |
| Short Label | hMSH3 |
| Category | organism-gene |
P20585 (MSH3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S30 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S33 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K98 | Acetylation | score1 | PhosphoSitePlus | |||
| K99 | Acetylation | score1 | PhosphoSitePlus | |||
| K103 | Acetylation | score1 | PhosphoSitePlus | |||
| K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S111 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K122 | Acetylation | score1 | PhosphoSitePlus | |||
| K123 | Acetylation | score1 | PhosphoSitePlus | |||
| K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S201 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y229 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y236 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K316 | Methylation | score1 | PhosphoSitePlus | |||
| K316 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S337 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T540 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T541 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K557 | Sumoylation | score1 | PhosphoSitePlus | |||
| K586 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K695 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K704 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K713 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K770 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K775 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K842 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K902 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T967 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S968 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 32387766 | ||
| T1054 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1068 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1074 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1091 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1099 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 20068231 | ||
| K1100 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S16 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S116 | F116 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| K122 | N122 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K178 | N178 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| K586 | T586 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K695 | N695 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K704 | E704 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K713 | T713 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K902 | Q902 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S968 | P968 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T1099 | M1099 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
DAG View