iPTMnet Report for P20340 (RAB6A)
Protein Information
UniProt AC / UniProt ID | P20340 / RAB6A_HUMAN |
Protein Name | Ras-related protein Rab-6A |
Gene Name | Name: RAB6A Synonyms:RAB6; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P20340 |
PRO Name | Ras-related protein Rab-6A (human) |
Definition | A Ras-related protein Rab-6A that is encoded in the genome of human. |
Short Label | hRAB6A |
Category | organism-gene |
P20340 (RAB6A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330, 20068231, 22814378, ... | ||
S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
T3 | Phosphorylation | score1 | PhosphoSitePlus | |||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y35 | Phosphorylation | score1 | PhosphoSitePlus | |||
S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
T54 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y56 | Phosphorylation | score1 | PhosphoSitePlus | |||
R60 | Methylation | score1 | PhosphoSitePlus | |||
T61 | Phosphorylation | score1 | PhosphoSitePlus | |||
T69 | Phosphorylation | score1 | PhosphoSitePlus | |||
S77 | Phosphorylation | score1 | PhosphoSitePlus | |||
R112 | Methylation | score1 | PhosphoSitePlus | |||
K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
S156 | O-Glycosylation | score1 | GlyGen | 33465208, 34229054 | ||
K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
K192 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S23 | N23 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y35 | F35 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
Y35 | C35 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
R60 | Q60 | Biomuta | DOID:4159 / skin cancer [ cosmic, cosmic ] | |
R112 | T112 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S156 | R156 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K164 | Q164 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |