iPTMnet Report for P20339 (RAB5A)
Protein Information
UniProt AC / UniProt ID | P20339 / RAB5A_HUMAN |
Protein Name | Ras-related protein Rab-5A |
Gene Name | Name: RAB5A Synonyms:RAB5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P20339 |
PRO Name | Ras-related protein Rab-5A (human) |
Definition | A Ras-related protein Rab-5A that is encoded in the genome of human. |
Short Label | hRAB5A |
Category | organism-gene |
P20339 (RAB5A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
R4 | Methylation | score1 | PhosphoSitePlus | |||
T7 | Phosphorylation | Q02156 (PRKCE) | score2 | PhosphoSitePlus | 24872409 | |
K22 | Acetylation | score1 | PhosphoSitePlus | |||
S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
C63 | Methylation | score1 | IEDB | 31844290 | ||
Y82 | Phosphorylation | score1 | PhosphoSitePlus | |||
S84 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 29125462 | ||
K116 | Ubiquitination | score1 | PhosphoSitePlus | |||
S123 | Phosphorylation | P27361 (MAPK3) | score3 | neXtProt PhosphoSitePlus | 10403367 | |
K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
R197 | Methylation | score1 | PhosphoSitePlus | |||
T202 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T205 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T208 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | G3 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
R4 | P4 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
R4 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T7 | K7 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
C63 | Y63 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K116 | N116 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S123 | N123 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K140 | E140 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |