iPTMnet Report for P20339 (RAB5A)
Protein Information
| UniProt AC / UniProt ID | P20339 / RAB5A_HUMAN |
| Protein Name | Ras-related protein Rab-5A |
| Gene Name | Name: RAB5A Synonyms:RAB5; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P20339 |
| PRO Name | Ras-related protein Rab-5A (human) |
| Definition | A Ras-related protein Rab-5A that is encoded in the genome of human. |
| Short Label | hRAB5A |
| Category | organism-gene |
P20339 (RAB5A) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R4 | Methylation | score1 | PhosphoSitePlus | |||
| T7 | Phosphorylation | Q02156 (PRKCE) | score2 | PhosphoSitePlus | 24872409 | |
| K22 | Acetylation | score1 | PhosphoSitePlus | |||
| S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C63 | Methylation | score1 | IEDB | 31844290 | ||
| Y82 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S84 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 29125462 | ||
| K116 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S123 | Phosphorylation | P27361 (MAPK3) | score3 | neXtProt PhosphoSitePlus | 10403367 | |
| K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R197 | Methylation | score1 | PhosphoSitePlus | |||
| T202 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T205 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T208 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S3 | G3 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| R4 | P4 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| R4 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| T7 | K7 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| C63 | Y63 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K116 | N116 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S123 | N123 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K140 | E140 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View