iPTMnet Report for P20333 (TNFRSF1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P20333 / TNR1B_HUMAN
Protein Name Tumor necrosis factor receptor superfamily member 1B precursor
Gene Name Name: TNFRSF1B
Synonyms:TNFBR,TNFR2;
Organism Homo sapiens (Human)

PRO ID PR:P20333
DAG View
PRO Name tumor necrosis factor receptor superfamily member 1B (human)
Definition A tumor necrosis factor receptor superfamily member 1B that is encoded in the genome of human.
Short Label hTNFRSF1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20333 (TNFRSF1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T30 O-Glycosylation GlyGen   UniProt 25456591
T206 O-Glycosylation GlyGen   UniProt 25456591
S208 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S221 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 25456591, 25813380
S221 Phosphorylation PhosphoSitePlus
T222 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 25456591, 25813380
T239 O-Glycosylation GlyGen 30459171
S248 O-Glycosylation GlyGen 25813380
S330 Phosphorylation PhosphoSitePlus   UniProt 23186163
T436 Phosphorylation phospho.ELM   PhosphoSitePlus 9535738
Site PTM Type PTM Enzyme Score Source PMID
S221 Phosphorylation HPRD 18491316
T436 Phosphorylation HPRD 9535738


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T222 R222 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T222 P222 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S248 I248 Biomuta DOID:363 / uterine cancer [ icgc ]
S330 F330 Biomuta DOID:4159 / skin cancer [ cosmic ]
T436 M436 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]