iPTMnet Report for P20226 (TBP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P20226 / TBP_HUMAN
Protein Name TATA-box-binding protein
Gene Name Name: TBP
Synonyms:GTF2D1,TF2D,TFIID;
Organism Homo sapiens (Human)

PRO ID PR:P20226
DAG View
PRO Name TATA-box-binding protein (human)
Definition A TATA-box-binding protein that is encoded in the genome of human.
Short Label hTBP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20226 (TBP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T114 O-Glycosylation GlyGen 34019948, 31866147
K181 Sumoylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
Y322 Phosphorylation PhosphoSitePlus
Y329 Phosphorylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000037194 (hCTNNB1/iso:1/Phos:9) increased Interaction PR:P20226 (hTBP) PRO 11279024


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T182 I182 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S261 I261 Biomuta DOID:1324 / lung cancer [ cosmic ]