Protein Information

Cytoscape View


UniProt AC / UniProt ID P20042 / IF2B_HUMAN
Protein Name Eukaryotic translation initiation factor 2 subunit 2
Gene Name Name: EIF2S2
Synonyms:EIF2B;
Organism Homo sapiens (Human)

PRO ID PR:P20042
DAG View
PRO Name eukaryotic translation initiation factor 2 subunit 2 (human)
Definition A eukaryotic translation initiation factor 2 subunit 2 that is encoded in the genome of human.
Short Label hEIF2S2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20042 (EIF2S2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
S2 Acetylation UniProt 19413330, 21406692, 22223895
S2 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18691976, 21406692, 23186163, ...17081983, 8024572, 16225457, 18452278, 19651622, 20068231
T11 Phosphorylation HPRD   PhosphoSitePlus 17081983
S13 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 8024572
T31 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18077418, 23186163
T33 Phosphorylation PhosphoSitePlus
T36 Phosphorylation PhosphoSitePlus   UniProt 23186163
S39 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
S67 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 21406692, 23186163, 8024572, ...16225457, 18452278, 19651622, 18669648, 20068231
K79 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
S105 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18452278, ...19651622, 18669648, 19690332, 20068231
T111 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 21406692, 23186163, ...18452278, 19651622, 18669648, 18707149, 19690332, 20068231
K124 Methylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
S158 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
R172 Methylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
K190 Acetylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S218 Phosphorylation P17612 (PRKACA) HPRD   neXtProt   PhosphoSitePlus 8024572
C226 S-Nitrosylation dbSNO 26338901
K227 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K265 Acetylation PhosphoSitePlus   UniProt 19608861
K265 Ubiquitination PhosphoSitePlus
K276 Acetylation PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
Y278 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
K293 Acetylation PhosphoSitePlus   UniProt 19608861
K293 Ubiquitination PhosphoSitePlus
R296 Methylation PhosphoSitePlus
Y298 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036242 (hEIF2S2/Ac:1) acM1 PRO