iPTMnet Report for P20023 (CR2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P20023 / CR2_HUMAN
Protein Name Complement receptor type 2 precursor
Gene Name Name: CR2
Synonyms:C3DR;
Organism Homo sapiens (Human)

PRO ID PR:P20023
DAG View
PRO Name complement receptor type 2 (human)
Definition A complement receptor type 2 that is encoded in the genome of human.
Short Label hCR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P20023 (CR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y108 Phosphorylation PhosphoSitePlus
N121 N-Glycosylation GlyGen   UniProt 12122212
N127 N-Glycosylation GlyGen   UniProt 12122212
T141 Phosphorylation PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
T209 Phosphorylation PhosphoSitePlus
K216 Acetylation PhosphoSitePlus
K225 Acetylation PhosphoSitePlus
C342 Methylation IEDB 31844290
C351 Methylation IEDB 31844290
Y506 Phosphorylation PhosphoSitePlus
N623 N-Glycosylation GlyGen   UniProt 24190977, 19349973
S782 Phosphorylation PhosphoSitePlus
N834 N-Glycosylation GlyGen 24190977
N861 N-Glycosylation GlyGen 24190977
N911 N-Glycosylation GlyGen 24190977
N962 N-Glycosylation GlyGen 24190977
C978 Methylation IEDB 31844290
T994 Phosphorylation PhosphoSitePlus
Y1024 Phosphorylation PhosphoSitePlus
Y1029 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Site PTM Type PTM Enzyme Score Source PMID
Y1029 Phosphorylation HPRD 18083107
Site PTM Type PTM Enzyme Score Source PMID
Y1088 Phosphorylation HPRD 18083107


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T145 I145 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T209 A209 Biomuta DOID:363 / uterine cancer [ icgc ]
T209 I209 Biomuta DOID:1324 / lung cancer [ cosmic ]
K225 N225 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S782 C782 Biomuta DOID:1324 / lung cancer [ cosmic ]
N861 H861 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]