iPTMnet Report P19438 TNFRSF1A

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P19438 / TNR1A_HUMAN
Protein Name	Tumor necrosis factor receptor superfamily member 1A precursor
Gene Name	Name: TNFRSF1A Synonyms:TNFAR,TNFR1;
Organism	Homo sapiens (Human)

PRO ID	PR:P19438 DAG View
PRO Name	tumor necrosis factor receptor superfamily member 1A (human)
Definition	A tumor necrosis factor receptor superfamily member 1A that is encoded in the genome of human.
Short Label	hTNFRSF1A
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P19438 (TNFRSF1A) as Substrate

Expanded View

Search:

	Site Select all By amino acid All Serine All Threonine All Tyrosine By position K48 K61 K64 S86 T90 T118 K242 K250 K265 Y318 K347 T353 Y360 S381 Y401 S402 T406 T411 T417	PTM Type Select all Phosphorylation Ubiquitination	PTM Enzyme	Score Select all 1 3	Source Select all IntAct PhosphoSitePlus RLIMS-P	PMID
	K48	Ubiquitination		score1	PhosphoSitePlus
	K61	Ubiquitination		score1	PhosphoSitePlus
	K64	Ubiquitination		score1	PhosphoSitePlus
	S86	Phosphorylation		score1	PhosphoSitePlus
	T90	Phosphorylation		score1	PhosphoSitePlus
	T118	Phosphorylation		score1	PhosphoSitePlus
	K242	Ubiquitination		score1	PhosphoSitePlus
	K250	Ubiquitination		score1	PhosphoSitePlus
	K265	Ubiquitination		score1	PhosphoSitePlus
	Y318	Phosphorylation		score1	PhosphoSitePlus
	K347	Ubiquitination		score1	PhosphoSitePlus
	T353	Phosphorylation		score1	PhosphoSitePlus
	Y360	Phosphorylation		score1	PhosphoSitePlus
	S381	Phosphorylation	O14920 (IKBKB)	score3	PhosphoSitePlus RLIMS-P	21724995
	Y401	Phosphorylation		score3	IntAct PhosphoSitePlus	11786908
	S402	Phosphorylation		score1	PhosphoSitePlus
	T406	Phosphorylation		score1	PhosphoSitePlus
	T411	Phosphorylation		score1	PhosphoSitePlus
	T417	Phosphorylation		score1	PhosphoSitePlus

Search:

	Site Select all By amino acid All Serine All Threonine By position S274 T280	PTM Type Select all Phosphorylation	PTM Enzyme	Score Select all 1	Source Select all HPRD	PMID
	S274	Phosphorylation	P28482 (MAPK1)	score1	HPRD	11606045
	T280	Phosphorylation	P28482 (MAPK1)	score1	HPRD	11606045

Proteoform PPIs

Search:

	Protein 1 Select all PR:000036504 (hTNF/iso:1/Clv:1)	Relation Select all Interaction	Protein 2 Select all PR:P19438 (hTNFRSF1A)	Source Select all PRO	PMID
	PR:000036504 (hTNF/iso:1/Clv:1)	Interaction	PR:P19438 (hTNFRSF1A)	PRO	14512626

PTM sites affected in variants

Search:

Site Select all By amino acid All Threonine By position T411 T417	Variant Select all M411 M417	Source Select all Biomuta	PMID	Disease [Sample source] Select all DOID:10283 / prostate cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
T411	M411	Biomuta		DOID:4159 / skin cancer [ cosmic ]
T417	M417	Biomuta		DOID:10283 / prostate cancer [ cosmic ]