iPTMnet Report for P19438 (TNFRSF1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P19438 / TNR1A_HUMAN
Protein Name Tumor necrosis factor receptor superfamily member 1A precursor
Gene Name Name: TNFRSF1A
Synonyms:TNFAR,TNFR1;
Organism Homo sapiens (Human)

PRO ID PR:P19438
DAG View
PRO Name tumor necrosis factor receptor superfamily member 1A (human)
Definition A tumor necrosis factor receptor superfamily member 1A that is encoded in the genome of human.
Short Label hTNFRSF1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P19438 (TNFRSF1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K48 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
Y318 Phosphorylation PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
T353 Phosphorylation PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
S381 Phosphorylation O14920 (IKBKB) PhosphoSitePlus   RLIMS-P 21724995
Y401 Phosphorylation IntAct   PhosphoSitePlus 11786908
S402 Phosphorylation PhosphoSitePlus
T406 Phosphorylation PhosphoSitePlus
T411 Phosphorylation PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S274 Phosphorylation P28482 (MAPK1) HPRD 11606045
T280 Phosphorylation P28482 (MAPK1) HPRD 11606045


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036504 (hTNF/iso:1/Clv:1) Interaction PR:P19438 (hTNFRSF1A) PRO 14512626


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T411 M411 Biomuta DOID:4159 / skin cancer [ cosmic ]
T417 M417 Biomuta DOID:10283 / prostate cancer [ cosmic ]