iPTMnet Report for P19429 (TNNI3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P19429 / TNNI3_HUMAN
Protein Name Troponin I, cardiac muscle
Gene Name Name: TNNI3
Synonyms:TNNC1;
Organism Homo sapiens (Human)

PRO ID PR:P19429
DAG View
PRO Name troponin I, cardiac muscle (human)
Definition A troponin I, cardiac muscle that is encoded in the genome of human.
Short Label hTNNI3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P19429 (TNNI3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 2226863
S5 Phosphorylation PhosphoSitePlus   UniProt 22972900
S6 Phosphorylation PhosphoSitePlus   UniProt 22972900
S23 Phosphorylation Q13976 (PRKG1) , P17612 (PRKACA) , Q15139 (PRKD1) , Q13131 (PRKAA1) , P17252 (PRKCA) , Q05655 (PRKCD) HPRD   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 24585778, 25296321, 18445579, ...22972900, 27557662, 20079745, 15134451, 8543035, 20164197, 19366211, 15514163, 24116014, 11724573, 26851561, 2226863, 21876643, 17854829, 23318976, 11056032, 23144315, 22456184, 27833092, 11904166, 9346285, 24772522, 18550549, 21959857, 32086378, 14596793, 20023122, 20079747, 11121119, 15769444
S24 Phosphorylation P17252 (PRKCA) , P17612 (PRKACA) , Q05655 (PRKCD) , Q15139 (PRKD1) , Q13976 (PRKG1) , Q13131 (PRKAA1) HPRD   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 25296321, 22972900, 27557662, ...14596793, 20023122, 8543035, 20164197, 19366211, 15514163, 24116014, 26851561, 2226863, 11121119, 17854829, 23318976, 11056032, 23144315, 22456184, 27833092, 11904166, 9346285, 24772522, 18550549, 21959857, 20079745, 24585778, 20079747, 21876643, 15769444, 15134451
Y26 Phosphorylation PhosphoSitePlus   UniProt 22972900
Y29 Phosphorylation PhosphoSitePlus
T31 O-Glycosylation GlyGen 23271734, 30379171
T31 Phosphorylation Q13043 (STK4) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18986304
S39 Phosphorylation P17612 (PRKACA) HPRD   neXtProt   PhosphoSitePlus 11121119
K40 Methylation PhosphoSitePlus
S42 Phosphorylation P05771 (PRKCB) , P17252 (PRKCA) , P05129 (PRKCG) HPRD   PhosphoSitePlus   RLIMS-P   Signor 15134451, 15769444, 2584239, ...24116014
S44 Phosphorylation P05771 (PRKCB) , P17252 (PRKCA) , Q02156 (PRKCE) , P05129 (PRKCG) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 15134451, 15769444, 2584239, ...24116014, 12551921
T51 Phosphorylation Q13043 (STK4) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18986304, 22972900
K72 Acetylation PhosphoSitePlus
R74 Methylation PhosphoSitePlus
S77 Phosphorylation P17252 (PRKCA) HPRD   PhosphoSitePlus   UniProt 2584239, 22972900
T78 Phosphorylation PhosphoSitePlus   UniProt 22972900
R79 Methylation PhosphoSitePlus
K106 Acetylation PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
T129 Phosphorylation Q13043 (STK4) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18986304
K131 Acetylation PhosphoSitePlus
T143 Phosphorylation Q05655 (PRKCD) , Q13043 (STK4) , P05771 (PRKCB) , P17252 (PRKCA) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18986304, 24585778, 18550549, ...19366211, 2584239, 24116014, 17010989, 22972900, 27557662
R146 Methylation PhosphoSitePlus
R148 Methylation PhosphoSitePlus
S150 Phosphorylation O75914 (PAK3) , Q13131 (PRKAA1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 12242269, 15769444, 22493448, ...22456184
S166 Phosphorylation P17612 (PRKACA) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21533915, 11121119, 22972900
K177 Acetylation PhosphoSitePlus
K178 Acetylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus   UniProt 22972900
K193 Acetylation PhosphoSitePlus
S199 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   RLIMS-P   UniProt 25771144, 24116014, 22972900


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049502 (hTNNI3/InitMet-/Phos:1) pS23,pS24 PRO