iPTMnet Report for P19235 (EPOR)
Protein Information
| UniProt AC / UniProt ID | P19235 / EPOR_HUMAN |
| Protein Name | Erythropoietin receptor precursor |
| Gene Name | Name: EPOR |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P19235 |
| PRO Name | erythropoietin receptor (human) |
| Definition | An erythropoietin receptor that is encoded in the genome of human. |
| Short Label | hEPOR |
| Category | organism-gene |
DAG ViewP19235 (EPOR) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S108 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S185 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y309 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y368 | Phosphorylation | O60674 (JAK2) , P07948 (LYN) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P | 27769065, 10579919 | |
| Y426 | Phosphorylation | score4 | IntAct phospho.ELM PhosphoSitePlus | 10660611, 7528537, 10579919, ... | ||
| T427 | Phosphorylation | score2 | IntAct | 7228577 | ||
| Y454 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus | 12027890, 10579919 | ||
| L455 | Phosphorylation | score2 | IntAct | 7228577 | ||
| Y456 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus | 11443118, 12027890, 10579919 | ||
| L457 | Phosphorylation | score2 | IntAct | 7228577 | ||
| Y468 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y485 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y489 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus | 9573010, 10579919 | ||
| Y504 | Phosphorylation | score4 | IntAct phospho.ELM PhosphoSitePlus | 9573010, 10579919, 7559499 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y368 | Phosphorylation | O60674 (JAK2) | score1 | HPRD | 12441334 | |
| Y426 | Phosphorylation | O60674 (JAK2) | score1 | HPRD | 12441334 | |
| Y454 | Phosphorylation | O60674 (JAK2) | score1 | HPRD | 12441334 | |
| Y456 | Phosphorylation | O60674 (JAK2) | score1 | HPRD | 12441334 | |
| Y468 | Phosphorylation | O60674 (JAK2) | score1 | HPRD | 12441334 | |
| Y485 | Phosphorylation | O60674 (JAK2) | score1 | HPRD | 12441334 | |
| Y489 | Phosphorylation | O60674 (JAK2) | score1 | HPRD | 12441334 | |
| Y504 | Phosphorylation | O60674 (JAK2) | score1 | HPRD | 12441334 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y426 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y426 | C426 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| T427 | N427 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| L457 | P457 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] |
