Protein Information

Cytoscape View


UniProt AC / UniProt ID P19022 / CADH2_HUMAN
Protein Name Cadherin-2 precursor
Gene Name Name: CDH2
Synonyms:CDHN,NCAD;
Organism Homo sapiens (Human)

PRO ID PR:P19022
DAG View
PRO Name cadherin-2 (human)
Definition A cadherin-2 that is encoded in the genome of human.
Short Label hCDH2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P19022 (CDH2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S61 Phosphorylation PhosphoSitePlus
S96 Phosphorylation UniProt 26091039
S135 Phosphorylation PhosphoSitePlus   UniProt 26091039
N273 N-Glycosylation UniProt 19159218
N402 N-Glycosylation UniProt 19159218
K448 Ubiquitination PhosphoSitePlus
T454 Phosphorylation PhosphoSitePlus
Y496 Phosphorylation PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
N572 N-Glycosylation UniProt 19159218
K667 Ubiquitination PhosphoSitePlus
T683 Phosphorylation PhosphoSitePlus
S685 Phosphorylation PhosphoSitePlus
N692 N-Glycosylation UniProt 19159218
K756 Ubiquitination PhosphoSitePlus
K772 Ubiquitination PhosphoSitePlus
Y773 Phosphorylation PhosphoSitePlus
Y785 Phosphorylation phospho.ELM   PhosphoSitePlus 16212419
S788 Phosphorylation PhosphoSitePlus
K802 Ubiquitination PhosphoSitePlus
Y820 Phosphorylation P12931 (SRC) PhosphoSitePlus 16371504
S824 Phosphorylation PhosphoSitePlus
Y852 Phosphorylation P12931 (SRC) phospho.ELM   PhosphoSitePlus   Signor 16371504
Y860 Phosphorylation P12931 (SRC) PhosphoSitePlus   RLIMS-P   Signor 16371504, 23292232, 24254198
Y884 Phosphorylation P12931 (SRC) phospho.ELM   PhosphoSitePlus   Signor 16371504
Y886 Phosphorylation P12931 (SRC) PhosphoSitePlus   Signor 16371504
Site PTM Type PTM Enzyme Score Source PMID
S135 Phosphorylation HPRD 18702456
Y785 Phosphorylation HPRD 16212419
S788 Phosphorylation HPRD 18077418


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S61 C61 Biomuta DOID:3571 / liver cancer [ tcga ]
T454 K454 Biomuta DOID:1324 / lung cancer [ tcga ]
Y496 F496 Biomuta DOID:4159 / skin cancer [ icgc ]
S685 L685 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc ]
S788 C788 Biomuta DOID:1324 / lung cancer [ tcga ]
K802 T802 Biomuta DOID:10534 / stomach cancer [ tcga ]
Y860 C860 Biomuta DOID:1324 / lung cancer [ cosmic ]