iPTMnet Report for P18545 (PDE6G)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P18545 / CNRG_HUMAN
Protein Name Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Gene Name Name: PDE6G
Synonyms:PDEG;
Organism Homo sapiens (Human)

PRO ID PR:P18545
DAG View
PRO Name retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (human)
Definition A retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma that is encoded in the genome of human.
Short Label hPDE6G
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P18545 (PDE6G) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T22 Phosphorylation P27361 (MAPK3) HPRD   PhosphoSitePlus 12624098
K25 Ubiquitination PhosphoSitePlus
R36 Methylation PhosphoSitePlus
T62 Phosphorylation A0A0S2Z3I6 (ADRBK1) , P25098 (GRK2) HPRD   phospho.ELM   Signor 11502744, 12624098


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K25 N25 Biomuta DOID:4159 / skin cancer [ cosmic ]
R36 S36 Biomuta DOID:10283 / prostate cancer [ cosmic ]