iPTMnet Report for P18507 (GABRG2)
Protein Information
UniProt AC / UniProt ID | P18507 / GBRG2_HUMAN |
Protein Name | Gamma-aminobutyric acid receptor subunit gamma-2 precursor |
Gene Name | Name: GABRG2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P18507 |
PRO Name | gamma-aminobutyric acid receptor subunit gamma-2 (human) |
Definition | A gamma-aminobutyric acid receptor subunit gamma-2 that is encoded in the genome of human. |
Short Label | hGABRG2 |
Category | organism-gene |
P18507 (GABRG2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y46 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y49 | Phosphorylation | score1 | PhosphoSitePlus | |||
K133 | Ubiquitination | score1 | PhosphoSitePlus | |||
S234 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y238 | Phosphorylation | score1 | PhosphoSitePlus | |||
T314 | Phosphorylation | score1 | PhosphoSitePlus | |||
S366 | Phosphorylation | Q02156 (PRKCE) | score4 | neXtProt phospho.ELM | 1321150, 17875639 | |
Y452 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y253 | Phosphorylation | score1 | PhosphoSitePlus | |||
S406 | Phosphorylation | P17252 (PRKCA) | score1 | HPRD | 1321150 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S234 | F234 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S234 | Y234 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
Y253 | N253 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T314 | I314 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T314 | K314 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |