Protein Information

Cytoscape View

UniProt AC / UniProt ID P18505 / GBRB1_HUMAN
Protein Name Gamma-aminobutyric acid receptor subunit beta-1 precursor
Gene Name Name: GABRB1
Organism Homo sapiens (Human)

PRO ID PR:P18505
DAG View
PRO Name gamma-aminobutyric acid receptor subunit beta-1 (human)
Definition A gamma-aminobutyric acid receptor subunit beta-1 that is encoded in the genome of human.
Short Label hGABRB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P18505 (GABRB1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K46 Ubiquitination PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
Y324 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S434 Phosphorylation P17612 (PRKACA) neXtProt   phospho.ELM   PhosphoSitePlus 1321150
S448 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S409 Phosphorylation HPRD 1321150, 1323140, 10195104
S448 Phosphorylation HPRD 17924679

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T85 A85 Biomuta DOID:363 / uterine cancer [ tcga ]
K127 T127 Biomuta DOID:5041 / esophageal cancer [ tcga ]
K127 N127 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S448 P448 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
S448 F448 Biomuta DOID:1909 / melanoma [ icgc, tcga ]