iPTMnet Report for P18084 (ITGB5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P18084 / ITB5_HUMAN
Protein Name Integrin beta-5 precursor
Gene Name Name: ITGB5
Organism Homo sapiens (Human)

PRO ID PR:P18084
DAG View
PRO Name integrin beta-5 (human)
Definition An integrin beta-5 that is encoded in the genome of human.
Short Label hITGB5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P18084 (ITGB5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T61 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
T199 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K206 Acetylation PhosphoSitePlus
C211 Methylation IEDB 31844290
K260 Ubiquitination PhosphoSitePlus
N347 N-Glycosylation GlyGen 29741879
N586 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N654 N-Glycosylation GlyGen 23090970, 24190977
T656 Phosphorylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus
K685 Ubiquitination PhosphoSitePlus
K756 Ubiquitination PhosphoSitePlus
S759 Phosphorylation O96013 (PAK4) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 20507994
S762 Phosphorylation O96013 (PAK4) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 20507994
Y766 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y774 Phosphorylation PhosphoSitePlus
K776 Ubiquitination PhosphoSitePlus
S779 Phosphorylation HPRD   PhosphoSitePlus 20068231
T780 Phosphorylation HPRD   PhosphoSitePlus 20068231
T782 Phosphorylation PhosphoSitePlus
T786 Phosphorylation PhosphoSitePlus
K792 Ubiquitination PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus
T797 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K206 T206 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
C211 W211 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
N586 K586 Biomuta DOID:3571 / liver cancer [ cosmic ]
T656 P656 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K756 N756 Biomuta DOID:363 / uterine cancer [ icgc ]
Y766 C766 Biomuta DOID:1324 / lung cancer [ cosmic ]
K776 T776 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T780 M780 Biomuta DOID:363 / uterine cancer [ icgc ]