iPTMnet Report for P18075 (BMP7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P18075 / BMP7_HUMAN
Protein Name Bone morphogenetic protein 7 precursor
Gene Name Name: BMP7
Synonyms:OP1;
Organism Homo sapiens (Human)

PRO ID PR:P18075
DAG View
PRO Name bone morphogenetic protein 7 (human)
Definition A bone morphogenetic protein 7 that is encoded in the genome of human.
Short Label hBMP7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P18075 (BMP7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K162 Ubiquitination PhosphoSitePlus
N187 N-Glycosylation GlyGen 24190977
T306 Phosphorylation PhosphoSitePlus
N321 N-Glycosylation GlyGen 24190977
S322 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
N372 N-Glycosylation GlyGen   UniProt 12667445, 12478285
Site PTM Type PTM Enzyme Score Source PMID
N372 N-Glycosylation PRO 8570652, 9872992, 15047707, ...15929982


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036421 (hNOG/iso:1/SigPep-) Interaction PR:000036517 (hBMP7/iso:1/mature/NGlyco:1) PRO 12478285
PR:P18075-1 (hBMP7/iso:1) Interaction PRO 12805376
PR:Q13873-1 (hBMPR2/iso:1) Interaction PR:P18075 (hBMP7) PRO 7791754


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K162 R162 Biomuta DOID:1612 / breast cancer [ cosmic ]
N187 I187 Biomuta DOID:10283 / prostate cancer [ cosmic ]
N321 S321 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
N372 S372 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]