iPTMnet Report for P18054 (ALOX12)
Protein Information
| UniProt AC / UniProt ID | P18054 / LOX12_HUMAN |
| Protein Name | Polyunsaturated fatty acid lipoxygenase ALOX12 |
| Gene Name | Name: ALOX12 Synonyms:12LO,LOG12; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P18054 |
| PRO Name | polyunsaturated fatty acid lipoxygenase ALOX12 (human) |
| Definition | A polyunsaturated fatty acid lipoxygenase ALOX12 that is encoded in the genome of human. |
| Short Label | hALOX12 |
| Category | organism-gene |
DAG ViewP18054 (ALOX12) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S244 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S246 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 | ||
| S249 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S255 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y395 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y551 | Phosphorylation | score1 | IEDB | 35494241 | ||
| S616 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T639 | O-Glycosylation | score1 | GlyGen | 30379171 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y295 | S295 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| T639 | A639 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
