iPTMnet Report for P17677 (GAP43)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P17677 / NEUM_HUMAN
Protein Name Neuromodulin
Gene Name Name: GAP43
Organism Homo sapiens (Human)

PRO ID PR:P17677
DAG View
PRO Name neuromodulin (human)
Definition A neuromodulin that is encoded in the genome of human.
Short Label hGAP43
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17677 (GAP43) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T36 Phosphorylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S41 Phosphorylation Q02156 (PRKCE) neXtProt   PhosphoSitePlus   RLIMS-P 16330713, 8263528, 18654638, ...1824693, 9133376, 2136704, 16212546, 8694767, 17326767, 11124896, 9622012, 25165142, 19249369, 10209246, 30778286
S96 Phosphorylation RLIMS-P 30240740
T107 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus   RLIMS-P 35347634, 30240740, 35608791
T144 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
T175 O-Glycosylation GlyGen 28657654
T181 Phosphorylation PhosphoSitePlus
K216 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation P05771 (PRKCB) HPRD 8694767, 2140056
S96 Phosphorylation HPRD 1533624
T107 Phosphorylation HPRD 18510355
S109 Phosphorylation HPRD 18510355
S142 Phosphorylation HPRD 18510355
S154 Phosphorylation HPRD 18510355
S202 Phosphorylation P68400 (CSNK2A1) HPRD 1828073
S203 Phosphorylation P68400 (CSNK2A1) HPRD 1828073


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S109 T109 Biomuta DOID:263 / kidney cancer [ cosmic ]
S131 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S142 N142 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S151 L151 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S154 F154 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T181 P181 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K216 E216 Biomuta DOID:4159 / skin cancer [ cosmic ]