iPTMnet Report for P17540 (CKMT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P17540 / KCRS_HUMAN
Protein Name Creatine kinase S-type, mitochondrial precursor
Gene Name Name: CKMT2
Organism Homo sapiens (Human)

PRO ID PR:P17540
DAG View
PRO Name creatine kinase S-type, mitochondrial (human)
Definition A creatine kinase S-type, mitochondrial that is encoded in the genome of human.
Short Label hCKMT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17540 (CKMT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y73 Phosphorylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S175 Phosphorylation HPRD 20068231
Y207 Phosphorylation PhosphoSitePlus
Y208 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
K281 Acetylation PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
R350 Methylation PhosphoSitePlus
T356 Phosphorylation PhosphoSitePlus
T361 Phosphorylation PhosphoSitePlus
Y368 Phosphorylation PhosphoSitePlus   RLIMS-P 34095014
S371 Phosphorylation PhosphoSitePlus
Y393 Phosphorylation PhosphoSitePlus
K419 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S148 L148 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K281 T281 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S319 L319 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
S343 C343 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y368 H368 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K419 N419 Biomuta DOID:1793 / pancreatic cancer [ icgc ]