iPTMnet Report for P17480 (UBTF)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P17480 / UBF1_HUMAN
Protein Name Nucleolar transcription factor 1
Gene Name Name: UBTF
Synonyms:UBF,UBF1;
Organism Homo sapiens (Human)

PRO ID PR:P17480
DAG View
PRO Name nucleolar transcription factor 1 (human)
Definition A nucleolar transcription factor 1 that is encoded in the genome of human.
Short Label hUBTF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P17480 (UBTF) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
M1 Acetylation UniProt 19413330
T9 Phosphorylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K61 Acetylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K114 Acetylation PhosphoSitePlus
K114 Sumoylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
T117 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 19103806, 11741541
T117 Phosphorylation P27361 (MAPK3) neXtProt   phospho.ELM   Signor 11741541
T117 Phosphorylation P28482 (MAPK1) neXtProt   phospho.ELM   Signor 11741541
K126 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K160 Sumoylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
T201 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32522876, 29351928, 34019948, 33465208, 28510447, 34229054, 29237092
T201 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18669648, 11741541, 19103806
T201 Phosphorylation P27361 (MAPK3) neXtProt   phospho.ELM   Signor 11741541
T201 Phosphorylation P28482 (MAPK1) neXtProt   phospho.ELM   Signor 11741541
Y207 Phosphorylation PhosphoSitePlus
T208 Phosphorylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
S229 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32522876, 29351928, 34019948, 33465208, 28510447, 34229054, 29237092
K232 Methylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K254 Methylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 17182730
K279 Sumoylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K284 Acetylation PhosphoSitePlus
K284 Sumoylation PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
C328 Methylation IEDB 31844290
S329 Phosphorylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
S336 Phosphorylation RLIMS-P 17182730
K338 Ubiquitination PhosphoSitePlus
K352 Acetylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 17182730
K378 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K385 Acetylation PhosphoSitePlus
T388 Phosphorylation PhosphoSitePlus
S389 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P 11698641, 10202152, 17182730
S389 Phosphorylation P24941 (CDK2) neXtProt   phospho.ELM 11698641, 10202152
S392 Phosphorylation PhosphoSitePlus
K394 Acetylation PhosphoSitePlus
K401 Acetylation PhosphoSitePlus
K406 Acetylation PhosphoSitePlus
S412 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 20068231, 17182730
K421 Ubiquitination PhosphoSitePlus
R429 Methylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus   RLIMS-P 17182730
S435 Phosphorylation PhosphoSitePlus   UniProt 23186163
R443 Methylation PhosphoSitePlus
S449 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32522876, 29351928, 34019948, 33465208, 28510447, 34229054, 29237092
S449 Phosphorylation PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
K464 Sumoylation PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
S484 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 11698641, 10202152, 17287340, ...21406692, 18669648, 33151228, 20068231, 17182730
S484 Phosphorylation P11802 (CDK4) neXtProt   phospho.ELM 10202152
S484 Phosphorylation P24941 (CDK2) neXtProt 11698641, 10202152
S495 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
Y500 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus   RLIMS-P 17182730
K559 Acetylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus   RLIMS-P 17182730
K594 Ubiquitination PhosphoSitePlus
S602 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
K624 Ubiquitination PhosphoSitePlus
S638 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 17182730
R642 Methylation PhosphoSitePlus
K646 Ubiquitination PhosphoSitePlus
Y648 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
S666 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation HPRD 18077418
T117 Phosphorylation HPRD 11741541
T117 Phosphorylation P27361 (MAPK3) HPRD 11741541
T117 Phosphorylation P28482 (MAPK1) HPRD 11741541
T201 Phosphorylation HPRD 18669648, 11741541, 19007248, ...20068231
T201 Phosphorylation P27361 (MAPK3) HPRD 18669648, 11741541, 19007248, ...20068231
T201 Phosphorylation P28482 (MAPK1) HPRD 18669648, 11741541, 19007248, ...20068231
S273 Phosphorylation HPRD 20068231
S389 Phosphorylation HPRD 11698641
S389 Phosphorylation P24941 (CDK2) HPRD 11698641
S412 Phosphorylation HPRD 18669648, 20068231
S449 Phosphorylation HPRD 20068231
S484 Phosphorylation HPRD 19413330, 10202152, 17287340, ...19007248, 18452278, 19651622, 18669648, 20068231, 19691289
S484 Phosphorylation P24941 (CDK2) HPRD 19413330, 10202152, 17287340, ...19007248, 18452278, 19651622, 18669648, 20068231, 19691289
S495 Phosphorylation HPRD 18669648, 20068231
S557 Phosphorylation HPRD 20068231
S638 Phosphorylation HPRD 18669648, 19007248, 20068231
S666 Phosphorylation HPRD 19651622
Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation HPRD 18077418
T201 Phosphorylation HPRD 18669648, 19007248, 20068231
T208 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S236 Phosphorylation HPRD 20068231
S375 Phosphorylation HPRD 18669648, 20068231
S412 Phosphorylation HPRD 20068231
S447 Phosphorylation HPRD 19413330, 17287340, 19007248, ...18452278, 19651622, 18669648, 20068231, 19691289
S458 Phosphorylation HPRD 18669648, 20068231
S520 Phosphorylation HPRD 20068231
S601 Phosphorylation HPRD 18669648, 19007248, 20068231
S629 Phosphorylation HPRD 19651622


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049591 (hUBTF/PhosRes+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K45 E45 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y150 H150 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T208 A208 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K211 N211 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S238 L238 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
K254 T254 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S306 * Biomuta DOID:4159 / skin cancer [ cosmic ]
C328 F328 Biomuta DOID:3571 / liver cancer [ cosmic ]
K624 N624 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R642 C642 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S655 T655 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]