iPTMnet Report for P17342 (NPR3)
Protein Information
| UniProt AC / UniProt ID | P17342 / ANPRC_HUMAN |
| Protein Name | Atrial natriuretic peptide receptor 3 precursor |
| Gene Name | Name: NPR3 Synonyms:ANPRC,C5orf23,NPRC; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P17342 |
| PRO Name | atrial natriuretic peptide receptor 3 (human) |
| Definition | An atrial natriuretic peptide receptor 3 that is encoded in the genome of human. |
| Short Label | hNPR3 |
| Category | organism-gene |
P17342 (NPR3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| N86 | N-Glycosylation | score4 | GlyGen UniProt | 16870210, 7727388 | ||
| S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N293 | N-Glycosylation | score4 | GlyGen UniProt | 11533490, 16870210, 7727388 | ||
| Y316 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N349 | N-Glycosylation | score2 | GlyGen | 7727388 | ||
| T392 | O-Glycosylation | score1 | GlyGen | 30620550 | ||
| N394 | N-Glycosylation | score4 | GlyGen UniProt | 11533490, 23090970, 16870210, ... | ||
| Y502 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K525 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S533 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N86 | S86 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S148 | * | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| S148 | L148 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ] | |
| S148 | P148 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S156 | L156 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| N293 | K293 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y316 | N316 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
DAG View