Protein Information

Cytoscape View

UniProt AC / UniProt ID P17275 / JUNB_HUMAN
Protein Name Transcription factor jun-B
Gene Name Name: JUNB
Organism Homo sapiens (Human)

PRO ID PR:P17275
DAG View
PRO Name transcription factor jun-B (human)
Definition A transcription factor jun-B that is encoded in the genome of human.
Short Label hJUNB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P17275 (JUNB) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K4 Sumoylation PhosphoSitePlus
K33 Sumoylation PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
K36 Sumoylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
Y47 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
K51 Sumoylation PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
S79 Phosphorylation Q16539 (MAPK14) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 15308641
T102 Phosphorylation P45983 (MAPK8) , Q16539 (MAPK14) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 9889198, 20068231, ...8917518
T104 Phosphorylation Q16539 (MAPK14) , P45983 (MAPK8) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 9889198, 8917518, ...20068231
Y109 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
S117 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T129 Phosphorylation PhosphoSitePlus
T153 Phosphorylation neXtProt 10790372
Y173 Phosphorylation P00519 (ABL1) PhosphoSitePlus   RLIMS-P 26217035
Y182 Phosphorylation P00519 (ABL1) PhosphoSitePlus   RLIMS-P 26217035
Y188 Phosphorylation P00519 (ABL1) PhosphoSitePlus   RLIMS-P 26217035
S189 Phosphorylation neXtProt 10790372
S237 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
K240 Acetylation PhosphoSitePlus
K240 Sumoylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
S251 Phosphorylation P49841 (GSK3B) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 22710716, 18452278, 19651622, ...18669648, 19690332, 20068231
T255 Phosphorylation P49841 (GSK3B) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...22710716, 18452278, 19651622, 18669648, 19690332, 20068231
S259 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18452278, 19651622, 18669648, 19690332
K304 Sumoylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
S311 Phosphorylation HPRD 20068231
S312 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P00533 (EGFR) S1039 P17275 (JUNB) decreased_association eFIP 24797263
Phosphorylation P17275 (JUNB) S79 Q09472 (EP300) unknown eFIP 15308641

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K4 E4 Biomuta DOID:363 / uterine cancer [ tcga ]
Y68 H68 Biomuta DOID:263 / kidney cancer [ icgc, tcga ]
T238 I238 Biomuta DOID:2531 / hematologic cancer [ icgc ]
T238 N238 Biomuta DOID:3571 / liver cancer [ icgc ]
S312 I312 Biomuta DOID:3571 / liver cancer [ icgc ]